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The science behind NovoSerum

NovoSerum: patented technology for topical cosmetic skincare.

NovoSerum is a proprietary, cell-free cosmetic ingredient derived from purified human umbilical cord serum, collected from volunteer donors after a healthy birth. It is the core ingredient in Novo Derma Post-Procedure Cream, a finished topical cosmetic product.

What it is made from

Responsibly sourced. Cell-free by design.

Umbilical cord serum is sourced through a U.S.-based cord blood bank operating under FDA regulations, then processed to remove cellular material. It contains no stem cells and no living cells.

What remains is a concentrate of approximately 350 total molecules, including proteins, cell signalers, nutrients, peptides and vitamins, formulated into a topical cosmetic cream.

Novo Derma is not sold or marketed as a peptide product or peptide therapy. It is also not an exosome product, cellular therapy, injectable or regenerative-medicine procedure.

Category

What Novo Derma is — and what it is not.

Novo Derma is

  • A finished topical cosmetic cream
  • Non-prescription and non-injectable
  • Professional post-procedure cosmetic aftercare
  • Sold through aesthetic practices in a 1.0 oz jar

Novo Derma is not

  • A drug, prescription product or medical device
  • An injection, infusion or administered therapy
  • An exosome, stem cell or cellular preparation
  • A wound care or regenerative-medicine product

Where Novo Derma fits

Novo Derma as cosmetic aftercare

Novo Derma Post Procedure Cream is a professional-grade topical cosmetic product designed to accompany the days that follow an aesthetic service. It gives clients a dedicated take-home step focused on hydration, comfort, skin appearance and a simple at-home routine.

NovoSerum mechanism

Research background, illustrated through the skin layers

This diagram illustrates the procollagen and GAG mechanism examined in the studied NovoSerum formulation. It is provided as research background, not as a consumer promise or expected outcome.

Cross-section diagram of the epidermis and dermis illustrating the studied NovoSerum procollagen and GAG mechanism

Research background

Research background on NovoSerum technology

In academic research conducted under double-blind conditions by Dr. Robert Lavker, Director of Dermatology Research at Northwestern University Medical School, each subject was treated on one site with the studied NovoSerum formulation and on the opposite site with vehicle only. The findings below describe that studied formulation and are provided as research background, not as a consumer promise or expected outcome.

Procollagen — studied formulation vs. vehicle only

SubjectChange
Subject 11.1% ↑
Subject 241.4% ↑
Subject 347.5% ↑
Subject 435.8% ↑
Subject 517.7% ↑
Subject 613.0% ↓

Reported change in 6 study subjects — average of approximately 28.7%.

GAGs — studied formulation vs. vehicle only

SubjectChange
Subject 180.0% ↑
Subject 243.0% ↑
Subject 358.7% ↑
Subject 416.7% ↓
Subject 537.8% ↑
Subject 622.3% ↑

Reported change in 6 study subjects — average of approximately 48.4%.

Research findings relate to the formulation studied in that academic research. Novo Derma Post-Procedure Cream is a topical cosmetic product and is not represented as providing any therapeutic or medical outcome.

Patent

Patented technology, applied to cosmetic skincare

NovoSerum is proprietary technology associated with U.S. Patent No. 8,790,710 B and supported by academic research. Novo Derma incorporates that technology into a finished, non-prescription topical cosmetic cream created for professional post-procedure aftercare in aesthetic practices.

U.S. Patent No. 8,790,710 B

Research foundation

A patented technology with an academic research foundation.

Proprietary & patented

NovoSerum is a patented serum technology (U.S. Patent No. 8,790,710 B) and the platform behind every Novo Derma formulation.

Responsible sourcing

Umbilical cord serum from volunteer donors after a healthy birth, sourced through a U.S.-based cord blood bank operating under FDA regulations.

Academic foundation

Double-blind research conducted by Dr. Robert Lavker, Director of Dermatology Research, Northwestern University Medical School.

Research & references

  • Double-blind academic research on NovoSerum technology conducted by Dr. Robert M. Lavker, Ph.D., Director of Dermatology Research, Northwestern University Medical School, Department of Dermatology.
  • U.S. Patent No. 8,790,710 B — the patented NovoSerum cosmetic technology behind every Novo Derma formulation.
  • Procedure-specific aftercare guidance: CO2 laser, microneedling, RF microneedling and chemical peels.
  • More materials for practices are collected in the professional resource hub.